Tobacco harms almost every organ of the body. It causes cancer, heart disease, stroke and lung disease, reduces fertility and weakens the immune system, and WHO states that there is no safe level of exposure to tobacco. According to WHO, tobacco kills more than 7 million people a year, including more than 1.6 million people who do not smoke themselves but are exposed to second-hand smoke. Nicotine is highly addictive, and WHO warns that it is particularly harmful for children, adolescents and young adults. Tobacco also deepens poverty, because money spent on it is taken from household budgets for food and housing.
An estimated 1.2 billion people aged 15 and older used tobacco in 2024, down from 1.38 billion in 2000, and around 80% of them live in low- and middle-income countries. More than four in five users are men. Adult use has fallen in every World Bank income group, from 33.1% of people aged 15 and older in 2000 to 19.5% in 2024, but the world will miss the goal of a 30% relative reduction between 2010 and 2025. At the same time, WHO's first global estimate counts more than 100 million people using e-cigarettes, including at least 15 million children aged 13 to 15.